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What is a gene? - Even scientists define 'a gene' in different ways, so it comes as little surprise that the media also have various ways of framing the concept of a gene, according to a new study appearing in the October 2008 issue of EMBO reports. ...
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Free drug samples may end up costing uninsured more - Free drug samples provided to physicians by pharmaceutical companies could actually be costing uninsured patients more in the long run, according to a study done by researchers at Wake Forest University Baptist Medical Center and colleagues. ...
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Old before their time? Aging in flies under natural vs. laboratory conditions - A marked T. angusticollis female on an Acacia trunk in Sydney. Evolutionary studies of aging typically utilize small, short-lived animals (insects, worms, mice) under benign conditions ? constant temperature and humidity, no parasites, superabundant food ? in the laboratory. Oddly enough, very little is known about aging in such animals in their harsh, stressful natural environments. Could it be that these laboratory "guinea pigs" actually age much more slowly in captive luxury than do their wild cousins? ...
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Recovery efforts not enough for critically endangered Asian vulture - Photos taken in Pakistan. Captive breeding colonies of a critically endangered vulture, whose numbers in the wild have dwindled from tens of millions to a few thousand, are too small to protect the species from extinction, a University of Michigan analysis shows. ...
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Atomic structure of the mammalian 'fatty acid factory' determined - Mammalian fatty acid synthase is one of the most complex molecular synthetic machines in human cells. It is also a promising target for the development of anti-cancer and anti-obesity drugs and the treatment of metabolic disorders. Now researchers at ETH Zurich have determined the atomic structure of a mammalian fatty acid synthase. Their results have just been published in Science magazine. ...
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Parsing the genome of a deadly brain tumor - The most comprehensive to-date genomic analysis of a cancer ? the deadly brain tumor glioblastoma multiforme ? shows previously unrecognized changes in genes and provides an overall view of the missteps in the pathways that govern the growth and behavior of cells, said members of The Cancer Genome Atlas Research Network in a report that appears online today in the journal Nature. ...
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Caught in a trap: bumblebees vs. robotic crab spiders - Bumblebees learn to avoid camouflaged predators by sacrificing foraging speed for predator detection, according to scientists from Queen Mary, University of London. ...
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Ancient DNA evidence points to woolly mammoths' dynamic past - The largest study ever conducted of DNA evidence extracted from long-dead woolly mammoths points to a rockier past for the iconic Ice Age giants than many had suspected. ...
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New 'trick' allows HIV to overcome a barrier to infection - Researchers have discovered a new 'trick' that allows HIV to overtake resting T cells that are normally highly resistant to HIV infection, according to a report in the September 5th issue of the journal Cell, a Cell Press publication. The binding of the virus to the surface of those cells sends a signal that breaks down the cells' internal skeleton, a structure that otherwise may present a significant barrier to infection. ...
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You can be replaced: Immune cells compensate for defective DNA repair factor - A new mouse model has provided some surprising insight into XLF, a molecule that helps to repair lethal DNA damage. The research, published by Cell Press in the September 5th issue of the journal Molecular Cell, suggests that although XLF shares many properties with well known DNA repair factors, certain cells of the immune system possess an unexpected compensatory mechanism that that can take over for nonfunctional XLF. ...
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Scientists reveal changes to embryonic stem cells caused by Down syndrome - Scientists investigating the mechanisms of Down Syndrome (DS) have revealed the earliest developmental changes in embryonic stem cells caused by an extra copy of human chromosome 21 ? the aberrant inheritance of which results in the condition. Their study is published online today (Thursday 4 September) in the American Journal of Human Genetics. ...
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Do 68 molecules hold the key to understanding disease? - Why is it that the origins of many serious diseases remain a mystery? In considering that question, a scientist at the University of California, San Diego School of Medicine has come up with a unified molecular view of the indivisible unit of life, the cell, which may provide an answer. ...
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Molecular evolution is echoed in bat ears - The big-eared horseshoe bat, Rhinolophus macrotis. Echolocation may have evolved more than once in bats, according to new research from the University of Bristol published this week in Proceedings of the National Academy of Sciences (PNAS). ...
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Gaining a better understanding of kidney diseases - Cystic kidney disease, renal fibrosis, or renal cell carcinoma: Many diseases of the excretory organs are characterized by overproduction or ? on the contrary ? absence of characteristic proteins in the renal cells. An international research team under the leadership of scientists from DKFZ and Heidelberg University Hospitals has now developed an animal model to better investigate these conditions. ...
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